Secreted Phospholipase A2Group X Overexpression in Asthma and Bronchial Hyperresponsiveness
نویسندگان
چکیده
منابع مشابه
Bronchial Hyperresponsiveness in Asthma*
Measurement ofnonspecific bronchial hyperresponsiveness remains largely a research tool in asthma, and its usefulness in the assessment and management of asthma is poorly defined. We StUdied the relationship of bronchial hyperresponsiveness to the clinical severity of asthma in 54 asthmatic subjects. In order to find out whether measurement of bronchial hyperresponsiveness could be used to pred...
متن کاملDetecting asthma and bronchial hyperresponsiveness in children.
The prevalence of asthma in children is increasing worldwide. Although the features of asthma are well documented, defining asthma remains a problem. The clinical definition of asthma does not take into account the concept of airway inflammation. A broader definition that incorporates the inflammatory process, reversibility of airway obstruction, and airway responsiveness needs to be more widel...
متن کاملAirway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma.
BACKGROUND There are few data in asthma relating airway physiology, inflammation and remodelling and the relative effects of inhaled corticosteroid (ICS) treatment on these parameters. A study of the relationships between spirometric indices, airway inflammation, airway remodelling, and bronchial hyperreactivity (BHR) before and after treatment with high dose inhaled fluticasone propionate (FP ...
متن کاملSmall Airway Impairment and Bronchial Hyperresponsiveness in Asthma Onset
PURPOSE Our study tried to find a relationship between baseline FEF25-75% and airway hyperresponsiveness (AHR) and whether a greater FEF25-75% impairment may be a marker of a more severe hyperresponsiveness in subjects with normal FEV1 and FEV1/FVC and suggestive asthma symptoms. Besides, we tried to asses a FEF25-75% cut-off value to identify hyper-reactive subjects. METHODS 4,172 subjects (...
متن کاملBronchial hyperresponsiveness and asthma in the paediatric population.
OBJECTIVE To determine whether the intensity of bronchial hyperresponsiveness (BHR) is correlated to other clinical data such as patient age at the onset of asthma, the serum IgE levels and familial genetic susceptibility, with the purpose of establishing a prognosis or phenotype. MATERIAL AND METHODS BHR was evaluated using the methacholine provocation test, with the patients divided into si...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2007
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.200707-1088oc